It's A Keto Life
Understanding the Keto Diet and How it Can Help You
Research on the Benefits of Keto

 

Evidence of Keto' Success  

 

Patient Outcome InfographicThis infographic shows patient reported outcomes on the ketogenic diet. Most patients reported improvements in their symptoms within the first six months. Infographic created by Nika Glover-Ward

Elsevier Science Ltd. published a study in 2012 comparing a low carb diet to a low carb ketogenic diet (LCKD). They studied 363 patients for 24 weeks. Of those, 102 of them had type 2 diabetes. They were given the option to try a low carb diet or LCKD. They found that the ketogenic diet appears to improve glycemic control. Therefore, diabetic patients on a ketogenic diet should be under strict medical supervision because the LCKD can significantly lower blood glucose levels, however the diet is considered effective because it has been show to significantly improve diabetes symptoms.

More than 170 million people across the globe have diabetes and it’s expected to reach 366 million by 2030 if people don’t change their eating habits. After long term administration, the ketogenic diet has been shown to alter the cardiac risk factor in obese patients and has been effective in decreasing anti-diabetic medication dosage.

 

 

How Keto Decreases Epilepsy and Possibly Helps with Autism


In a 2013 study researchers found that, BTBR mice fed a standard diet exhibit neither spontaneous seizures nor abnormal EEG, and have increased seizure susceptibility in just one of four tests. Thus, behavioral improvements are dissociable from any antiseizure effect. The results suggest that a ketogenic diet improves multiple autistic behaviors in the BTBR mouse model. Therefore, ketogenic diets or analogous metabolic strategies may offer novel opportunities to improve core behavioral symptoms of autism spectrum disorders.


Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and communication deficits. Incidence is rising, and current treatments are inadequate. Seizures are a common comorbidity, and since the 1920's a high-fat, low-carbohydrate ketogenic diet has been used to treat epilepsy. Evidence suggests the ketogenic diet and analogous metabolic approaches may benefit diverse neurological disorders. Here we show that a ketogenic diet improves autistic behaviors in the BTBR mouse. Juvenile BTBR mice were fed standard or ketogenic diet for three weeks and tested for sociability and they were successfully improved. 

 


Reduction of Chronic Inflammation

 

A 2017 study conducted at the University of California San Francisco found that reduced glucose metabolism activated a protein called CtBP which acted to suppress the activity of inflammatory genes. Lead researcher Raymond Swanson, MD, stated: “I was most surprised by the magnitude of this effect because I thought ketogenic diets might help just a little bit. But when we got these big effects… I thought wow, there’s really something here.”



Keto Inflammation Article

Article from University of California SanFrancisc reports on how the ketogenic diet has helped to reduce inflammation. Image courtesy UCSF.





Visual Guide to the Ketogenic Process


Metabolic pathways of the ketogenic dietThis image from pg. 50 of the book Dietary Treatment of Epilepsy demonstrates what happens to the body during ketosis.





Percentage of Patient Improvements Over Time



 

Patient OutcomesThis pie chart, from pg. 26 of the book Dietary Treatment of Epilepsy demonstrates patient reported outcomes on the success of the keto diet.